Melanotan II (MT-II) is a synthetic cyclic heptapeptide analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). It functions as a potent non-selective agonist of endogenous melanocortin receptors, including MC1R, MC3R, MC4R, and MC5R, making it a pivotal subject in peptide binding assays and receptor kinetics research.
Essential Aminos provides Melanotan II as a lyophilized powder prepared under controlled laboratory conditions to ensure exceptional purity and consistency across experimental trials. In research models, it is evaluated for its role in melanocortin pathway signaling, receptor activation profiles, and peptide structural stability.
Molecular & Chemical Profile
CAS Number:
121062-08-6
Molecular Weight:
1024.18 g/mol
Chemical Formula:
C50H69N15O9
Sequence / Structure:
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Alternate Names:
Melanotan 2
MT-II / MT-2
Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Frequently Asked Questions
What is Melanotan II?
It is a synthetic cyclic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH) utilized in scientific literature to investigate melanocortin receptor binding affinity and intracellular signal transduction.
Which receptors does Melanotan II interact with in research models?
In experimental assays, Melanotan II exhibits non-selective agonist properties across several melanocortin receptor subtypes, primarily targeting MC1R, MC3R, MC4R, and MC5R.
What is the chemical formula and molecular weight of Melanotan II?
Melanotan II has a chemical formula of C50H69N15O9, a molecular weight of 1024.18 g/mol, and is cataloged under CAS #121062-08-6.
How should Melanotan II lyophilized powder be stored in the laboratory?
For long-term stability, lyophilized peptide vials should be stored at desiccated temperatures (-20°C or below), protected from direct light exposure prior to reconstitution for analytical testing.
What are the primary research applications of Melanotan II?
Scientific literature focuses on evaluating Melanotan II in receptor cross-reactivity studies, peptide structural stability assays, and physiological pathway responses controlled by the melanocortin system.
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Disclaimer: All compounds and research materials provided by Essential Aminos are strictly for laboratory and research professional use only. They are not approved for human or animal use nor consumption by the Food and Drug Administration (FDA). These products should not be used for any form of in vivo experimentation or for any other non-laboratory purpose. Any violation or indication of human or animal use will result in immediate removal from being able to purchase products in the future. By purchasing these products, you acknowledge that they will be used exclusively within a controlled and qualified research environment.
Certificate of Analysis
Certificates of analysis are provided for laboratory research reference. Expand a batch below to view the PDF. Only the newest three COAs for this product are listed here.
